解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Segment 10, encoding nonstructural proteins 3 (NS3) and 3a (NS3a) of epizootic haemorrhagic disease virus serotype 1 (EHDV-1) was sequenced. Computer motif recognition programs were used for interpretation of the sequence data to predict a structure for NS3. Integral membrane protein theories were then applied to prod...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309968
更新日期:1995-01-01 00:00:00
abstract::The effect of temperature on the response of tomato (Lycopersicon esculentum Mill. cv. Rutgers) to infections with the necrogenic cucumber mosaic virus (CMV) satellite D-CARNA 5 was investigated with each of four CMV strains D, 1, Y and S functioning as helper virus. At 24 degrees C lethal necrosis was observed in all...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309724
更新日期:1995-01-01 00:00:00
abstract::Synthetic peptides comprising the predicted principal neutralizing determinant (PND) in new African and North American HIV-1 clones were tested in ELISA for reactivity with ninety six serum samples from asymptomatic donors in six selected localities in Uganda. Irrespective of the geographical origin of the samples, th...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322666
更新日期:1995-01-01 00:00:00
abstract::We analyzed retrospectively a relative risk of measles attacks in vaccinated vs. unvaccinated students using two independent outbreaks in Japan. The first involved 33/328 (10%) students where 64% students and 30% measles cases had been vaccinated. The second involved 27/241 (11%) students where 81% students and 48% me...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309868
更新日期:1995-01-01 00:00:00
abstract::cDNA clones spanning the entire region of the peplomer (S) gene of feline infectious peritonitis virus (FIPV) type I strain KU-2 were obtained and their complete nucleotide sequences were determined. A long open reading frame (ORF) encoding 1464 amino acid residues was found in the gene, which was 12 residues longer t...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718424
更新日期:1995-01-01 00:00:00
abstract::We focused on the role of membrane bound sugar residues in the infection of fibroblasts and monocyte-like cells with human cytomegalovirus (HCMV). Treatment of phorbol 12-myristate 13-acetate (PMA) differentiated monocyte-like cells THP-1 or human fibroblasts MRC-5 with lectins specific for N-acetylneuraminic acid (Ne...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322663
更新日期:1995-01-01 00:00:00
abstract::A polymerase chain reaction (PCR) based assay capable of detecting and differentiating seven strains of equine arteritis virus (EAV) from around the world was developed. The primers for the PCR were chosen from the ORF6 gene encoding the unglycosylated membrane protein (M). Viral RNA from cell culture fluids infected ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322675
更新日期:1995-01-01 00:00:00
abstract::By means of indirect immunofluorescence assay (IFA) using natural swine immune serum and hyperimmune serum from rabbits infected with porcine circovirus (PCV), a PCV antigen was detected present prior to the onset of viral and cellular DNA synthesis in nucleoli of cells of synchronized and growth stimulated infected P...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01384343
更新日期:1995-01-01 00:00:00
abstract::The interaction between two different bovine respiratory syncytial virus (BRSV) strains and bovine alveolar macrophages (BAMs) was studied in vitro. Bovine respiratory syncytial virus replicated minimally in BAMs and most of the virus produced remained cell-associated. Approximately 1 out of 1,000 BAMs produced infect...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322681
更新日期:1995-01-01 00:00:00
abstract::The amino acid sequences of the regions encoding the structural proteins of eleven nepoviruses and five comoviruses, two genera of the family Comoviridae, have been aligned. The properties predicted by computer analysis (three-dimensional-3D-structure, hydrophobicity) are also correlated along this alignment, and alig...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322691
更新日期:1995-01-01 00:00:00
abstract::The full length gene for the coat protein (CP) of the potyvirus, Johnsongrass mosaic virus, was incorporated into recombinant baculovirus and expressed in insect cells. Western blot and Coomassie-stained polyacrylamide gel electrophoresis analysis of infected insect cells demonstrated that CP was produced in large qua...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01321065
更新日期:1994-01-01 00:00:00
abstract::Genetic heterogeneous mouse populations selected for high (HIII) and low (LIII) antibody response were used to study some aspects of mouse hepatitis virus 3 (MHV3) infection, such as the resistance pattern, virus replication in the liver and peritoneal exudate or in cultured peritoneal macrophages, the interferon (IFN...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309475
更新日期:1994-01-01 00:00:00
abstract::Tunicamycin inhibited the production of infectious Borna disease virus (BDV) and glycosidase treatment eliminated the infectivity of cell-free virus. A glycoprotein of approximately 17 kDa, found in association with infectious virus, was identified by Concanavalin A binding. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309486
更新日期:1994-01-01 00:00:00
abstract::Treatment of a mouse macrophage cell line Mk1 with pokeweed mitogen (PWM) either before or during but not after virus inoculation resulted in an enhancement of dengue virus (DV) infection. The infection enhancement was primarily due to an increase in the number of DV-infected cells but not to increased virus productio...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379106
更新日期:1994-01-01 00:00:00
abstract::We investigated the transforming domain of a recently isolated feline sarcoma virus (TP1-FeSV) which encodes a fgr-related tyrosine kinase expressed as a gag-fgr fusion protein. The gag portion was removed and replication-competent expression vectors (RCAS) with inserted v-fgr sequences were established. Chicken embry...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379113
更新日期:1994-01-01 00:00:00
abstract::Sixteen patients with symptoms typical for Ockelbo disease (rash, arthralgia, fever) were enrolled in a 2 1/2 year study, during which clinical symptoms were recorded and ELISA was employed to study specific IgM, IgG and IgG subclass development. Initially, all patients presented with rash and arthralgia, and five pat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379107
更新日期:1994-01-01 00:00:00
abstract::We constructed a recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2E delta 102). The production, processing and transportation of the recombinant protein in baculovirus-infected Spodoptera frugiperda (Sf9) cells and its immunogenic prop...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309465
更新日期:1994-01-01 00:00:00
abstract::The mechanism of cell death induced by feline immunodeficiency virus (FIV) infection was investigated in an interleukin 2(IL-2)-dependent T-lymphoblastoid cell line (MYA-1). DNA extracted from FIV-infected MYA-1 cells showed a ladder of nucleosomal DNA, indicating that the cytopathic effect (CPE) observed in these cel...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309772
更新日期:1994-01-01 00:00:00
abstract::Human cytomegalovirus (HCMV), oxidized by sodium periodate (NaIO4), is incapable of giving rise to viral progeny in cell culture. At a NaIO4 concentration as low as 5 mM, there is a loss of at least 6 logs of viral infectivity which occurs very rapidly (less than 5 min). Further, the inactivation is a first-order reac...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309765
更新日期:1994-01-01 00:00:00
abstract::In our attempt to isolate mutant cell lines resistant to Newcastle disease virus (NDV) we developed an improved procedure for enrichment of NDV-resistant cells from mouse FM3A cells and isolated a novel NDV-resistant mutant cell line, Had-2, with characteristics different from Had-1, a previously reported NDV-receptor...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310796
更新日期:1994-01-01 00:00:00
abstract::The present work shows that at least four different sequence types of Aleutian mink disease parvovirus (ADV) are present in ADV isolates from mink. We here report the nucleotide sequences of these four types of ADV from nucleotide 123 to 2208 (map unit 3 to 46). This part of the genome encodes three non-structural (NS...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379127
更新日期:1994-01-01 00:00:00
abstract::The genetic and antigenic diversity of group A rotaviruses recovered from Israeli infants has been expanded recently by the inclusion of three unusual human rotavirus strains. Two rotavirus strains (Ro-5829 and Ro-5960) were shown to be the first viruses outside Japan that resembled the AU-1 genogroup of feline like h...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379138
更新日期:1994-01-01 00:00:00
abstract::Reverse transcription coupled with the polymerase chain reaction (RT-PCR) was used for the rapid laboratory diagnosis of pestivirus infections. A direct DNA sequencing method was developed for the analysis of the amplified cDNA from the 5' noncoding region of the viral genome. 70 pestivirus strains were compared in th...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309467
更新日期:1994-01-01 00:00:00
abstract::Non-structural as well as VP1 recombinant proteins of foot-and-mouth disease virus (FMDV) produced in E. coli, have been used to study the specific antibody response of infected or vaccinated swine. An analysis of sera from infected pigs, using a direct ELISA, showed that polypeptide 3ABC (spanning non-structural prot...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01538822
更新日期:1994-01-01 00:00:00
abstract::To characterize the role of the humoral immune response on HIV-1 infection of monocytes and macrophages (M phi s) we examined the susceptibility of in vitro cultured monocyte/M phi s to various HIV-1 isolates and the influence of heterologous and particularly autologous anti HIV-1 sera on this infection. Depending on ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01538815
更新日期:1994-01-01 00:00:00
abstract::Complementary oligonucleotide primers which flank a 1146-nucleotide gene fragment (S1B: nt 1185 to 2333) encompassing a polymorphic region (nt 1368 to 1776) of the S1 subunit of bovine coronavirus spike glycoprotein were used for enzymatic amplification by PCR. We chose four clinical isolates, recovered from cases of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310017
更新日期:1994-01-01 00:00:00
abstract::Expression of the entire open reading frame of hepatitis A virus was achieved in a vaccinia virus/T7/EMCV hybrid system. The expressed antigens were characterized as particles with buoyant densities and sedimentation coefficients typical of empty capsids and pentamers of HAV. This was further confirmed by electron mic...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310029
更新日期:1994-01-01 00:00:00
abstract::Structural analysis of the US-segment of a viable temperature sensitive human cytomegalovirus mutant (ts9) by the use of restriction enzymes, specific amplifications by the polymerase chain reaction and DNA sequencing, revealed deletions of open reading frames (orf) US14 and part of US15 in addition to that concerning...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311183
更新日期:1994-01-01 00:00:00
abstract::Translation of poliovirus RNA is initiated by entry of ribosomes into the nucleotide sequence (internal ribosomal entry site; IRES) within the 5'-untranslated region (5'-UTR). Efficiency of this translation initiation in rabbit reticulocyte lysates (RRL) was very low and was greatly enhanced by addition of the ribosom...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310034
更新日期:1994-01-01 00:00:00
abstract::Mouse cell lines (L, NIH3T3, and RMA cells) infected with the Edmonston strain of measles virus (MV) did not exhibit cytopathic effects (CPE), consistent with the finding that mice are not susceptible to MV. Northern blot analysis, however, revealed that MV genes were transcribed in infected L and NIH3T3 cells, althou...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310037
更新日期:1994-01-01 00:00:00
abstract::Site-directed mutagenesis was used to study the biological significance of three N-linked glycans (linked to Asn406, Asn448, and Asn463), situated in the CD4-binding region of gp120. Mutagenesis was carried out in a phage M13 system, and the mutated env genes were inserted into recombinant vaccinia virus (r-vaccinia v...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310571
更新日期:1994-01-01 00:00:00
abstract::Restriction maps of cervid herpesviruses 1 and 2 which are antigenetically related to bovine herpesvirus 1, were deduced from Southern blot hybridization with HindIII restriction fragments of BHV-1 DNA as probes. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309448
更新日期:1993-01-01 00:00:00
abstract::Influenza virus A/WSN/33 forms large plaques (> 3 mm diameter) on MDCK cells whereas A/Aichi/2/68 forms only small plaques (< 1 mm diameter). Fast growing reassortants (AWM), isolated by mixed infection of MDCK cells with these two virus strains in the presence of anti-WSN antibodies, all carried the M gene from WSN. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313769
更新日期:1993-01-01 00:00:00
abstract::Intravenous polyoma virus inoculation into pregnant Wistar rats resulted in transplacental infection of the foetus, causing tumours and hydronephroses. Cyclosporin A reduced these effects significantly. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313783
更新日期:1993-01-01 00:00:00
abstract::BALB/c mice developed contralateral necrotizing retinitis following intracameral inoculation with herpes simplex virus type 1 (HSV-1). The animals showed a positive delayed-type hypersensitivity (DTH) response at 10 days postinoculation, indicating that the anterior chamber-associated immune deviation was transient af...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309535
更新日期:1993-01-01 00:00:00
abstract::The porcine paramyxovirus LPM recognizes alpha, but not beta, anomers of sialic acid containing structures, specifically sialyl (alpha 2,3) lactose. The virus specificity is directed to the sialyl residue and to the C'4 axial OH and the C'6 CH2OH of the galactose present in this structure. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309755
更新日期:1993-01-01 00:00:00
abstract::Studies on rotavirus non-structural proteins have been hampered in the past by difficulties in obtaining monospecific reagents. To make such reagents available, we have expressed in the baculovirus system NSP2 and NSP3 (formerly called NS35 and NS34, respectively) of the bovine rotavirus RF and produced hybridomas aga...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309746
更新日期:1993-01-01 00:00:00
abstract::Scrapie and Creutzfeldt-Jakob disease (CJD) are caused by infectious agents that are defined phenomenologically. No agent-specific molecules or particles have been identified. Biological properties, such as exponential agent replication and strain variation, as well as physical characteristics of infectivity indicate ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309662
更新日期:1993-01-01 00:00:00
abstract::Complete nucleotide sequences of cytoplasmic inclusion (CI) genes of two strains of potato virus Y (PVY) were determined from six polymerase chain reaction (PCR)-amplified cDNA clones. The size of the CI genes of both ordinary (PVY-O) and necrotic strains (PVY-T13) was 1902 nucleotides, with a sequence homology of 83....
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309785
更新日期:1993-01-01 00:00:00
abstract::The DNAs from nine Japanese field isolates of equine herpesvirus-1 (EHV-1) were analyzed by digestion with the restriction endonuclease Bam HI and Southern hybridization. Comparing restriction profiles among the EHV-1 strains, there was no considerable difference between isolates before and after vaccine application, ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316881
更新日期:1993-01-01 00:00:00